These reactions are generally mild and self-limiting, representing a common adverse effect rather than a serious safety concern
These effects of Pycnogenol on joints can be explained by previous findings, showing that regular intake of Pycnogenol leads to a potent decrease of pro-inflammatory markers like NF-B and COX-enzymes, as well as a decline in the release of matrix metallopeptidase (MMP) enzymes, that are responsible for destroying cartilage in joints (71)
Staying hydrated and eating smaller, more frequent meals can also help manage these symptoms
You may find that you naturally skip snacks you would have previously eaten or feel satisfied with significantly smaller portions at meals
[169], asterripeptides A-C, which are marine fungal tripeptides that include a cinnamic acid moiety, were investigated for their wound healing capacity in S
Then there's the prospect of ineffective contraception